Hairy cell leukemia. Clinical recommendations
نویسندگان
چکیده
منابع مشابه
The clinical evaluation of hairy cell leukemia.
It seems to be well established by now that hairy cell leukemia (HCL) patients in apparent complete remission may harbor residual hairy cells in their bone marrow demonstrable only by immunohistologic and not by routine morphologic Recently, Pangalis et a13,4 and Catovsky et al’ reported splenic infiltration with hairy cells in HCL patients treated with interferona2b who before splenectomy were...
متن کاملClinical staging system for hairy-cell leukemia.
To find a clinical staging system for patients with hairy cell leukemia, 391 patients contributed by 22 centers were analyzed using the proportional hazard survival model. Attention was paid to nonsplenectomized patients to find a staging system to predict the survival length at the time of diagnosis. On the basis of hemoglobin level and spleen size at the time of diagnosis, 3 stages could be d...
متن کاملHairy cell leukemia: short review, today's recommendations and outlook
Hairy cell leukemia (HCL) is part of the low-grade non-Hodgkin lymphoma family and represents approximately 2% of all leukemias. Treatment with splenectomy and interferon-α historically belonged to the first steps of therapeutic options, achieving partial responses/remissions (PR) in most cases with a median survival between 4 and 6 years in the 1980s. The introduction of the purine analogs (PA...
متن کاملHairy cell leukemia-variant.
Hairy cell leukaemia variant is a very rare chronic lymphoproliferative disorder and is closely related to hairy cell leukemia. We hereby describe a case of hairy cell leukaemia variant for the first time in Saudi Arabia. An elderly Saudi man presented with pallor, massive splenomegaly, and moderate hepatomegaly. Hemoglobin was 7.7 g/dl, Platelets were 134 x109/l and white blood count was 140x1...
متن کاملHairy Cell Leukemia in a Young Male: An Unusual Presentation
Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and hepatomegaly (liver span - 16.9 cm). However, no lymphadenopathy was found.
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ژورنال
عنوان ژورنال: Journal of Modern Oncology
سال: 2020
ISSN: 1815-1442,1815-1434
DOI: 10.26442/18151434.2020.1.200063